Omega-3 fatty acids
- Omega-3 polyunsaturated fatty acids are chemicals found in fish and some nut and vegetable oils that are an essential part of a healthy diet.
- The purpose of this study is to test omega-3 fatty acids (fish oil), an over-the-counter nutritional supplement, vs. placebo (olive oil) in people with dry eye disease.
- Omega-3 fatty acids are typically used to treat hypertriglyceridemia (high levels of fat in the blood) and are currently being studied to determine their effects on various problems of the eye.
- Their usefulness in treating dry eye disease has not been established, although many sufferers from dry eyes self-medicate with Omega 3 to relieve their symptoms—without the efficacy and safety of their use being established.
- Patients in the DREAM Study will take 5 capsules a day of either Omega-3 or olive oil.
- The Omega 3 capsules contain 400 mg EPA and 200 mg DHA (two types of fatty acids), and patients assigned to Omega-3 will be taking 5 times that amount, i.e., 2000 mg EGA and 1000 mg DHA.
- Patients may be taking up to 1200 mg EPA and DHA in addition to the study supplements.